Peptidase - ορισμός. Τι είναι το Peptidase
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Τι (ποιος) είναι Peptidase - ορισμός

ENZYME THAT CATALYZES PROTEOLYSIS, BREAKING DOWN PROTEINS INTO SMALLER POLYPEPTIDES OR SINGLE AMINO ACIDS
Proteinase; Proteases; Proteolytic enzyme; Proteolytic Enzyme; Peptidase; Peptide hydrolases; Protease la; PABI; Protease accumulated by inhibitors; E1101; Proteolytic enzymes; Neutral proteases; Neutral protease; Acid protease; Acid proteinase; Peptidases; Proteinases
  • polarise]] water, which then hydrolyses the substrate. The bottom panel shows 2-step hydrolysis where a residue within the enzyme is activated to act as a [[nucleophile]] (Nu) and attack the substrate. This forms an intermediate where the enzyme is covalently linked to the N-terminal half of the substrate. In a second step, water is activated to hydrolyse this intermediate and complete catalysis. Other enzyme residues (not shown) donate and accept hydrogens and electrostatically stabilise charge build-up along the reaction mechanism.
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Protease         
A protease (also called a peptidase or proteinase) is an enzyme that catalyzes (increases reaction rate or "speeds up") proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. They do this by cleaving the peptide bonds within proteins by hydrolysis, a reaction where water breaks bonds.
protease         
['pr??t?e?z]
¦ noun Biochemistry an enzyme which breaks down proteins and peptides.
Origin
early 20th cent.: from protein + -ase.
proteinase         
['pr??ti:ne?z]
¦ noun Biochemistry an enzyme which breaks peptide bonds other than terminal ones in a peptide chain.

Βικιπαίδεια

Protease

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes (increases reaction rate or "speeds up") proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. They do this by cleaving the peptide bonds within proteins by hydrolysis, a reaction where water breaks bonds. Proteases are involved in many biological functions, including digestion of ingested proteins, protein catabolism (breakdown of old proteins), and cell signaling.

In the absence of functional accelerants, proteolysis would be very slow, taking hundreds of years. Proteases can be found in all forms of life and viruses. They have independently evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms.

Παραδείγματα από το σώμα κειμένου για Peptidase
1. Both drugs are members of the same class, known as DDP–4 (dipeptidyl peptidase–4) inhibitors.